Advertising Shimla: Two days after gangrape, no arrests, cops mum on probe Shimla: Modi factor may work for BJP Solan building collapse: 11 more bodies retrieved, death toll 14 Related News The bodies of 12 Army personnel and a civilian were extricated from the debris, the officials said. (Express Photo by Pradeep Kumar)The death toll in the building collapse incident on the Kumarhatti-Nahan highway in Solan district mounted to 14 after eleven more bodies were retrieved from the debris on Monday. The 14 dead included 13 Army personnel and one civilian. Moreover, all the 42 people — 30 Army personnel and 12 civilians — who were trapped in the debris were pulled out after night-long rescue operations by the Army, Central Reserve Police Force (CRPF) and police, ANI reported.Death toll in Solan building collapse rises to 13However, Rohit Rathore, Solan Sub Divisional Magistrate, said the actual number of those trapped inside would be clear only after the rescue operation ends in the evening.IN PICS | Building collapses in SolanChief Minister Jai Ram Thakur, who visited the spot on Monday morning, said prima facie the structure was not built up to the specifications. “A magisterial inquiry has already been ordered. Strict legal action will be taken against erring persons after getting the report,” PTI quoted Thakur as saying. An FIR was registered against the owner of the building, he said. By Express Web Desk |New Delhi | Updated: July 15, 2019 4:58:47 pm “There are more such buildings in the state. Owners have constructed them without following building by-laws. Whatever is required to be done, will be done to check it,” he said. Chief Minister Jai Ram Thakur, who visited the spot on Monday morning, said prima facie the structure was not built up to the specifications. (Express photo)Director-cum-Special Secretary Revenue and Disaster Management DC Rana told PTI that two National Disaster Response Force (NDRF) teams from Haryana’s Panchkula and Shimla’s Sunni reached the spot late in the night to carry out the rescue work. An NDRF team from Panchkula joined on Monday morning, he added.Locals said soldiers of the 4 Assam regiment had come to the Sehaj Tandoori Dhaba, housed in the building, for a meal hosted by some JCOs. Sources at the Dharampur Police Station said 30 Army personnel and around a dozen others were inside the restaurant.The building was owned by one Sahil, and initial reports said he was getting some extension work done on it. He had leased out a part of it for the restaurant. Both Sahil and the dhaba owner were not in the building at the time of the collapse. Advertising Post Comment(s)
Apparently, we’ve been making babies well over the last couple of decades, because this year millennials are set to replace boomers, my group, as the most powerful buying audience.Given their age, they certainly are the primary target group for game consoles. Millennials want the firms they buy from to be much more socially and environmentally aware and to play well with others, according to the surveys I’ve seen.That seems to translate well into the idea that they want to be able to connect with their friends on the platforms they buy, regardless of the platforms their friends are on. While millennials aren’t the European Commission, they are vastly more powerful. Although they can’t impose a fine, they can choose the companies they buy from, and they increasingly are unlikely to buy from firms that have implemented a lock-in model.This kind of means Apple (which ties together products like the iPhone and Apple Watch and clearly doesn’t support interoperability) is likely going to be screwed in the long term. We’ve known for some time that Apple’s core customer base is more boomer than millennial anyway. The Millennial Market The Interoperability Issue It amazes me how often firms feel they need to learn another company’s lessons the hard way. The rules are simple: Listen to the customers, do what they want, and you’ll do well; don’t and you won’t.Microsoft was far from the first to mess up, and Sony and Apple will be far from the last. It just seems that given unemployment and layoffs are not a ton of fun, more firms would learn from the mistakes of others and not do things that would cost them the market.Given that Sony already gave Microsoft the market once, you’d think it would make doubly sure not to do it again. Apparently not… It has days of battery life, while the new Apple Watch lasts a fraction of a day. The Motiv Ring it does its one thing well. The Apple Watch runs a small number of apps, but it has connectivity issues. The Motiv Ring is easy to use — the Apple Watch, not so much. (The Wall Street Journal, which used to be one of Apple’s biggest fans, recently published a review concluding that the new watch was unusable.)Given that both products generally are bought primarily by folks interested in their fitness functions, much like Microsoft’s Zune and Apple’s iPod were bought to listen to music, it is ironic that the Motiv Ring comes closer to Steve Jobs’ successful minimalist approach than his company’s product.The Motiv Ring is an attractive, easy to use, simple way to monitor your fitness, and you don’t have to change out your watch or whatever you use for portable music. It doesn’t try to be a micro-smartphone or do a ton of stuff that you likely don’t need done.It does one thing, and it does that one thing well. It monitors your exercise — oh, and it focuses on time active not just steps, which generally is thought to be a better metric. Because it has days of battery life, you can use the sleep tracker function.Because the Motiv Ring reminds me of what Apple used to be when it was near magical, at US$200 (or about half the price of the new Apple Watch 3) it is my product of the week. Microsoft has learned a lot of very hard lessons over the last couple of decades, and it continues to surprise and annoy me that other firms seem to have the suicidal tendency to learn the same lessons the hard way.My view is that it is far better and cheaper to avoid the mistakes of others, but firms like Apple, Google and, most recently, Sony seem to want to cherry-pick past Microsoft disasters and experience them first hand. The latest issue has to do with interoperability and millennials.Both Nintendo and Microsoft are perfectly happy if games play on multiple systems, but Sony has a cow at the very hint of the idea. I think this attitude eventually will doom the PlayStation, particularly given that the new Xbox One X already appears to be the more desirable product this holiday.I’ll explain and then close with my product of the week: the Motiv Ring, which turns out to be a better — and more Steve Jobs’ Apple-like — solution than the Apple Watch. (And yes, the Apple Watch also repeats a Microsoft mistake). Sony’s latest blunder came to light last week when PS4 Fortnite players were having a great time playing with their friends on Xbox.You see, while both Microsoft and Nintendo don’t have a problem with this kind of thing, Sony hates it. After it became clear that developers could enable this capability — one that both PlayStation and Xbox users want — the Sony pulled the plug with prejudice. Yes, Sony will let you play with a friend on a PC, but it won’t let you play with someone on another console.What this means is that in group play, the folks with the Xbox or Nintendo Switch might have an advantage. The folks on the PlayStation therefore are likely to switch to the competing console and abandon the inferior products.Of course, by blocking interoperability, Sony implies that it knows it has an inferior product and is using lock-in to prevent users from moving between platforms.The risk is that players may conclude they’ll have more people to play with on the Switch and Xbox platforms, and get upset with Sony for this decision to push users away from the PlayStation platform.This is in sharp contrast to what Microsoft learned and is executing with the Xbox: If you decide to compete and open your platform rather than locking people down on it, and if you build a better product, then folks will flock to you. This practice does force the firm using it to build better products. This all lies on top of the Xbox One X’s allegedly superior performance and better timing. You see, the PlayStation 4 Pro has been in the market for a while and now doesn’t seem that new or exclusive.As we move toward the holidays, the Xbox One X, which isn’t shipping yet, is likely to be the more exclusive product, making it more desirable in any case. Tack onto that the fact that it will be more interoperable, because that is Microsoft’s focus, and it looks like a winner — particularly with millennials, who may decide that they’d rather play with more friends than support a platform from a firm that doesn’t listen to them, which historically has been problem with Sony. Xbox One X Advantage Rob Enderle has been an ECT News Network columnist since 2003. His areas of interest include AI, autonomous driving, drones, personal technology, emerging technology, regulation, litigation, M&E, and technology in politics. He has undergrad degrees in merchandising and manpower management, and an MBA in human resources, marketing and computer science. He is also a certified management accountant. Enderle currently is president and principal analyst of the Enderle Group. He formerly served as a senior research fellow at Giga Information Group and Forrester. Email Rob. MotivRing Sony’s PlayStation Screw-Up Speaking of repeating Microsoft mistakes, remember Zune? Microsoft wanted to take the market away from the iPod, which at the time did one thing (play music) really well. Its solution could play video, but it didn’t have videos to play. It could share music if both parties had Zunes and a music subscription — and in its initial configuration, it looked like a brown turd.The Motiv Fitness Ring, compared to the Apple Watch, has a similar dynamic. It does one thing well — it monitors your fitness activity. While game systems exist in the consumer market, Microsoft’s big lesson in interoperability came last decade when the European Commission demanded that the company interoperate. Like anyone else that is ordered to do something, it first objected strenuously. For me, it came to a head when the father of then modern Windows, Jim Allchin dropped by my house for a chat.He told me that begrudgingly, Microsoft was going to give in to the EC’s demands, but that it would charge any customer that wanted access to Microsoft’s APIs (application programing interfaces) a massive amount for that access — because, well, Microsoft really didn’t want to interoperate. It believed that interoperability would open it to competition, and that it would lose its market.I looked at Jim and asked, “do you really think the European Commission is made up of idiots?”Having spent some time in litigation, I knew that a U.S. judge, seeing a similar action from a firm, likely would throw the book at it. To Microsoft’s credit, it realized its error and pivoted. Instead of resisting interoperability, it decided to become the best at it. It would make its stuff work better with competitors’ platforms then their competitors would.Rather than declining, sales increased, because buyers started to consider Microsoft as a better hub. Its interoperability skill meant that related problems generally reflected badly on the very firms that claimed they wanted interoperability but really didn’t want to do it.You see, Microsoft’s initial response was right in a way. The firms that had complained to the EU wanted to use the interoperability issue to replace Microsoft products — but instead they often found that because they weren’t sincere, they got replaced instead. There is a tone of irony there. Wrapping Up
Source:https://wistar.org/news/press-releases/age-related-changes-skin-structure-and-lymphatic-system-permeability-promote Reviewed by James Ives, M.Psych. (Editor)Oct 3 2018Changes in the structure of the skin and the lymphatic system that occur with the natural aging process create permissive conditions for melanoma metastasis, according to two studies by The Wistar Institute. These changes are caused by loss of the HAPLN1 protein, which is part of the extracellular matrix, during aging. The studies were published back-to-back in Cancer Discovery.Older age is a negative prognostic factor for melanoma, associated with higher frequency of development of incurable distant metastasis. Ashani Weeraratna, Ph.D., Ira Brind Professor, and professor and co-leader of the Immunology, Microenvironment and Metastasis Program at Wistar, and team have a long-standing focus on how aging affects the melanoma microenvironment, or the tumor’s ecosystem that includes immune cells, fibroblasts, blood and lymphatic vessels, and signaling molecules, to understand how age-related changes contribute to tumor progression and therapy resistance.In these new studies, the Weeraratna Lab and collaborators characterized architectural changes that occur in the extracellular matrix (ECM) in the skin and surrounding the lymphatic vessels, which promote the spread of melanoma cells to distant sites by influencing tumor cell and immune cell trafficking. They also discovered a fundamental role played by the HAPLN1 protein in the molecular mechanisms underlying these changes.In one study, the researchers focused on ECM produced by fibroblasts in the dermal layer of the skin and observed dramatic changes in expression levels of many ECM proteins, particularly HAPLN1.”The same structural changes that happen in our skin with aging and cause the appearance of wrinkles are also responsible for the increased risk of metastasis in older melanoma patients,” said Weeraratna, senior author in both studies. “With advancing age, the network of fibers that supports our skin loses the ‘basket weave’ organization that is characteristic of younger skin, and becomes looser. In a tumor setting, we think of it as a barrier that helps contain the tumor cells by inhibiting their motility while favoring infiltration of immune cells into the tumor mass. In older patients, due to the loss of HAPLN1, this barrier becomes less efficient.”Related StoriesScientists reveal mechanism of tumor metastasis and tumor-suppressive role of UDP-glucoseMathematical model helps quantify metastatic cell behaviorUAMS-developed noninvasive device detects melanoma in earliest stagesBy manipulating expression levels of HAPLN1 in three-dimensional human skin reconstruct models and in mouse skin models, Weeraratna and colleagues showed that loss of HAPLN1 creates a permissive microenvironment that favors escape of tumor cells while hampering trafficking of antitumor immune cells, particularly CD8+ T cells. Accordingly, injection of recombinant HAPLN1 around the tumor in melanoma mouse models reduced the size and metastatic capability of the tumor.In the second study, Weeraratna and colleagues showed that age-associated loss of lymphatic vessel integrity allows melanoma cells to escape more easily the lymphatic system and the proximal lymph nodes to reach distant sites. Results showed that this process, too, is associated with loss of HAPLN1, which causes a similar scenario to that described in the skin: degradation of the extracellular matrix in which the lymphatic vessels are embedded and reduced anchorage of lymphatic endothelial cells to their structural support, which results in increased permeability.”It is known that older individuals with melanoma have a lower incidence of lymphatic metastasis than younger patients yet higher rates of distant visceral metastasis,” said Weeraratna. “Our observation that older lymphatic vessels and lymph nodes are less efficient as a barrier to contain the metastatic cells may underlie that observation.”In this setting, injection of recombinant HAPLN1 into the draining lymph nodes of aged melanoma-bearing mice increased the rates of lymphatic micrometastases while reducing the frequency of lung metastasis, suggesting that containment of the metastatic cells in the local lymphatic system may have therapeutic implications when coupled to surgical resection of the sentinel lymph nodes.Taken together, the two studies support a novel, fundamental role for HAPLN1 as a prognostic factor for long-term survival and a potential new therapeutic avenue.
Reviewed by James Ives, M.Psych. (Editor)Nov 15 2018Toby Lewsadder stepped outside an Ace Hardware store wearing a simple one-strap dust mask. He knew it wasn’t the right defense against the wildfire smoke lingering in the air, but it was all he could find.The local hardware stores he checked Tuesday didn’t have the more substantial respirator mask that public health officials recommend to defend against the harmful wildfire smoke that is blanketing communities across the state. One pharmacy he contacted was selling surgical masks for only a quarter.”No one has them,” said Lewsadder, 41, who was visiting the state capital from Los Angeles for an IT conference. So, for now, the dust mask would have to do: “Something is better than nothing,” he said.Unfortunately, Lewsadder is wrong.The type of mask you wear matters very much if you don’t want to inhale harmful pollutants, experts say.And as deadly fires burn in Northern and Southern California, destroying communities and lives, millions of people outside the burn zones are exposed to the dangerous smoke that’s billowing into their communities and settling like dark shrouds.Wildfire smoke is dangerous because it contains fine particulates that can lodge deep into the lungs, which can cause or worsen respiratory issues, such as asthma. Some groups are especially vulnerable, including children and older people.The particulate matter floating across much of Northern California in the past week has registered more than 18 times the recommended levels by the World Health Organization. Such levels can trigger acute symptoms like difficulty breathing and headaches — even in otherwise healthy people.Health experts agree that the best defense is to stay indoors.But many also suggest that if you must go outside for a prolonged period, it’s best to wear the right kind of mask — especially if you have a health condition such as asthma, heart problems or emphysema.Health professionals and firefighters are fitted for the right mask, but the general public is not.So what kind of mask is the best?Not the dust mask that Lewsadder was wearing. Or the surgical masks that loop around your ears. Forget wearing a bandana or holding a tissue over your mouth — those won’t protect your lungs.The California Governor’s Office of Emergency Services and the California Department of Public Health recommend “N95” respirators or “P100″ masks, both of which are approved by the National Institute for Occupational Safety and Health for health care workers and firefighters.Those simple-but-sophisticated masks are intended to block at least 95 percent of the hazardous and tiny particulate matter — known as PM2.5 — that spews from wildfire smoke. At 2.5 microns or less in diameter, the particles of PM2.5 can’t even be seen by the naked eye, said Dr. John Balmes, a professor of environmental health sciences at the University of California-Berkeley. (For comparison, a human hair can measure as little as 16 microns in diameter.)Once you find the right kind of mask, it’s also important to wear it correctly:The mask should have two straps. One strap should be placed below the ears and one above. And the mask should seal tightly to your face.”The efficiency of the mask is all about how well it fits the contours of your face,” said Keith Bein, an associate professional researcher with the Air Quality Research Center at the University of California-Davis. “If there’s a gap, air will come through the gap.”But if you have difficulty breathing or become dizzy, remove the mask.When a disposable mask gets dirty inside or you have trouble breathing, throw it out.Related StoriesNew network for children and youth with special health care needs seeks to improve systems of careResearch sheds light on sun-induced DNA damage and repairRevolutionary gene replacement surgery restores vision in patients with retinal degenerationTo the worry of some parents, the N95 masks aren’t small enough for most children. Balmes, a medical doctor, said he tells his colleagues that they can put adult masks on their children, but he can’t promise they will work.In Sacramento, since the Camp Fire devastated the Sierra Nevada foothills town of Paradise about 90 miles north, the typically blue skies appear overcast. In reality, it’s a smoky haze that has settled over the trees and buildings, leaving an acrid taste in people’s mouths and irritating their eyes.Air-quality levels in the region have been in the “unhealthy,” “very unhealthy” or “hazardous” ranges for much of the week.Area residents have received mixed messages about whether to wear masks. Sacramento County’s public health division issued a statement saying that only those people living near the fire should wear masks because they restrict airflow and can make it more difficult to breathe. Meanwhile, the city of Sacramento is distributing free masks to the public at fire stations.”There is confusion, and I think one of the problems is there is not enough evidence-based medicine on whether healthy individuals should be putting on these masks and when it’s effective,” said Mary Prunicki, a medical researcher and instructor at Stanford University’s Sean N. Parker Center for Allergy & Asthma Research. “That’s something we’re actually trying to investigate.”Despite the mixed messages and poor air quality, many people in the state capital appear to be going about their business as usual. Leland Gilmore, 77, who was walking his dog, Ruff, in McKinley Park near downtown, didn’t think the smoke “was bad enough” to stay inside. Neither did the people shooting hoops, playing tennis and jogging at the same park.”I’m concerned, yes, but I’m not taking any special measures,” said Gail Peoples, 61, on her late-morning walk with her two dogs. “This time of day seems OK.”However, Peoples said she is worried about older family members, like her mother-in-law who has pulmonary issues and hasn’t left the house for a week.Peoples knows there’s a special mask but doesn’t know what she should look for.When Sisco Martinez, who doesn’t suffer from any asthma or respiratory issues, felt some chest pain, he visited a Sacramento fire station for a mask.”I work indoors, but still, I wasn’t feeling too well, so I thought I’d better go get one,” said Martinez, 19.Experts acknowledge that the masks don’t block all the toxins in the air — the chemical gases, for example, released into the atmosphere when fire engulfs neighborhoods and the construction materials, cars, paint and other consumer goods that people use every day.”The masks are only removing particulate matter,” Bein said. “It doesn’t remove the toxic gases.”Still, Bein said, the proper masks are “still working better than nothing.”This story was produced by Kaiser Health News, which publishes California Healthline, a service of the California Health Care Foundation. This article was reprinted from khn.org with permission from the Henry J. Kaiser Family Foundation. Kaiser Health News, an editorially independent news service, is a program of the Kaiser Family Foundation, a nonpartisan health care policy research organization unaffiliated with Kaiser Permanente.
Source:https://www.usc.edu/ Reviewed by James Ives, M.Psych. (Editor)Mar 6 2019What if a special diet could reduce inflammation and repair your gut?USC researchers provided evidence that a low-calorie “fasting-mimicking” diet has the potential to do just that. Published in the March 5 edition of Cell Reports, the study reports on the health benefits of periodic cycles of the diet for people with inflammation and indicated that the diet reversed inflammatory bowel disease (IBD) pathology in mice.Results showed that fasting-mimicking diet caused a reduction in intestinal inflammation and an increase in intestinal stem cells in part by promoting the expansion of beneficial gut microbiota. Study authors say the reversal of IBD pathology in mice, together with its anti-inflammatory effects demonstrated in a human clinical trial, indicate that the regimen has the potential to mitigate IBD.”This study for the first time combines two worlds of research,” said Valter Longo, a study author and the director of the USC Longevity Institute at the USC Leonard Davis School of Gerontology and professor of biological sciences at the USC Dornsife College of Letters, Arts and Sciences. “The first is about what you should eat every day, and many studies point to a diet rich in vegetables, nuts and olive oil. The second is fasting and its effects on inflammation, regeneration and aging.”By combining these fields of research using the fasting-mimicking diet, the authors were able to reduce the inflammation and pathology associated with intestinal diseases.Longo said for people with a poor diet, a “once in a while” fix is the periodic use of a low-calorie, plant-based diet that causes cells to act like the body is fasting. Earlier clinical trials conducted by Longo and colleagues allowed participants to consume between 750 and 1,100 calories per day over a five-day period and contained specific proportions of proteins, fats and carbohydrates. Participants saw reduced risk factors for many life-threatening diseases.”Fasting is hard to stick to and it can be dangerous,” Longo said. “We know that the fasting-mimicking diet is safer and easier than water-only fasting, but the big surprise from this study is that if you replace the fasting-mimicking diet, which includes pre-biotic ingredients, with water, we don’t see the same benefits.”In the study, one group of mice adhered to a four-day fasting-mimicking diet by consuming approximately 50 percent of their normal caloric intake on the first day and 10 percent of their normal caloric intake from the second through fourth days. Another group fasted with a water-only diet for 48 hours.Related StoriesHigh-fat, low-carbohydrate diet may improve brain function and memory in older adultsStudy reveals link between inflammatory diet and colorectal cancer riskWhat happens when you eliminate sugar and adopt the keto diet?The study demonstrated that two cycles of a four-day fasting-mimicking diet followed by a normal diet appeared to be enough to mitigate some, and reverse other, IBD-associated pathologies or symptoms. In contrast, water-only fasting came up short, indicating that certain nutrients in the fasting-mimicking diet contribute to the microbial and anti-inflammatory changes necessary to maximize the effects of the fasting regimen.”We’ve determined that the dietary components are contributing to the beneficial effects; it’s not just about the cells of the human body but it’s also about the microbes that are affected by both the fasting and the diet,” Longo said. “The ingredients in the diet pushed the microbes to help the fasting maximize the benefits against IBD.”The research team observed activation of stem cells and a regenerative effort in the colon and the small intestine, which increased significantly in length only in the presence of multiple cycles of the fasting-mimicking diet. They concluded that fasting primes the body for improvement, but it is the “re-feeding” that provides the opportunity to rebuild cells and tissues.”It is really remarkable, that in the past 100 years of research into calorie restriction, no one recognized the importance of the re-feeding,” Longo said. “Restriction is like a demolition where you take the building down. But you have to rebuild it. If you don’t do that, there’s no benefit. You are left with an empty lot, and what have you achieved?”In the current and previous studies, the authors showed that in patients with elevated C-reactive protein (CRP), a marker for inflammation, fasting-mimicking diet cycles are able to reduce CRP and reverse the associated increase in white blood cells. Together with the results in mice, these data indicate that fasting-mimicking diet cycles have the potential to be effective against human IBD, including Crohn’s disease and ulcerative colitis.IBD afflicts an estimated 1.6 million Americans and is associated with acute and chronic inflammation of the intestine. Study authors say a randomized clinical trial involving the use of fasting-mimicking diet cycles to treat IBD is necessary to determine the safety and efficacy of these dietary treatments in humans, and are currently finalizing a clinical trial protocol.
Reviewed by James Ives, M.Psych. (Editor)May 10 2019The Gale and Graham Wright Prostate Centre at North York General Hospital (NYGH) is advancing prostate cancer care with a new study that shows the benefits of transperineal prostate biopsies (TPBx) under local anesthetic.Published online in the Journal of Urology the study, “Transperineal Prostate Biopsies Using Local Anesthesia: Experience in 1,287 Patients. Prostate Cancer Detection Rate, Complications and Patient Tolerability” provides evidence that the TPBx approach for testing and diagnosing prostate cancer is accurate and has significantly fewer complication rates compared to the traditional prostate biopsy method.Related StoriesSpecial blood test may predict relapse risk for breast cancer patientsStudy: Nearly a quarter of low-risk thyroid cancer patients receive more treatment than necessaryHow cell-free DNA can be targeted to prevent spread of tumors”After performing more than a thousand TPBx procedures under local anesthetic, the team at North York General has shown that it is the safest method of obtaining a biopsy for prostate cancer and patients tolerate the procedure well,” said Dr. Stan Flax, NYGH urologist and one of the study’s lead authors. “The clinical data provides the necessary evidence that the medical community needs in order to move toward a new standard of care for patients.”In 2016, NYGH’s Gale and Graham Wright Prostate Centre became the first in Canada to use the TPBx approach, which involves obtaining the biopsy using a needle through the skin. Studies have shown that TPBx is a safer alternative for patients, as compared to transrectal biopsies, due to the lower risk of serious infections, which can result in hospitalization and admission to an intensive care unit.In the very few settings where TPBx is performed, the procedure is done using general or spinal anesthetic, which typically requires more intensive resources. For the past three years, urologists at NYGH have exclusively used TPBx under local anesthetic and have tracked a total of 1,287 procedures as part of this study. The data shows this method of prostate biopsies has the same accuracy rate, if not better as transrectal, compared to the team’s previous series of transrectal biopsies.Prostate cancer is the most commonly diagnosed cancer among North American men, with approximately one in seven men being diagnosed with this disease in their lifetime. It is also one of the more treatable cancers, if detected and treated in its early stages.”Only one percent of testing for prostate cancer in North America is done using TPBx,” says Dr. Flax. “Given how often prostate biopsies are performed, there is a real opportunity to improve patient care with our research.” Source:http://www.nygh.on.ca/Default.aspx?cid=4756&lang=1
Reviewed by James Ives, M.Psych. (Editor)Jun 24 2019Temperature-related mortality has been decreasing in Spain over the past four decades, according to a new study led by the Barcelona Institute for Global Health (ISGlobal), a research center supported by “la Caixa”. The study analyzed the Spanish population’s vulnerability to hot and cold temperatures in the context of global warming.The study, published in The Lancet Planetary Health, analyzed temperatures and deaths related to cardiovascular diseases recorded in 48 Spanish provinces between 1980 and 2016. Cardiovascular diseases are the leading cause of death in Spain and there is clear evidence of an association between temperature and cardiovascular mortality.The findings show that temperature-related cardiovascular disease mortality was 38.2% lower in the period between 2002 and 2016 than for the period between 1980 and 1994. Analysis of the data in 15-year periods revealed that temperature-related cardiovascular mortality decreased at a rate of more than 17% per decade.Specifically, heat-related cardiovascular mortality for the period 2002-2016 was more than 42% lower in men and more than 36% lower in women than in 1980-1994, while cold-related mortality was 30% lower in women and nearly 45% lower in men.Notable differences were observed between the sexes: heat-related mortality was much higher in women, while men were more vulnerable to cold temperatures. In older people, the risk of death attributable to high temperatures was significantly higher for both sexes, but in the case of cold the increase was significant only for men.”We observed two parallel phenomena,” explained Hicham Achebak, a researcher at ISGlobal and the Centre for Demographic Studies (CED) and lead author of the study. “First, over the past four decades the mean temperature has risen by nearly 1°C. The trend is towards fewer days of moderate or extreme cold temperatures and more days of high temperatures. Second, the Spanish population has adapted to both cold and warm temperatures. The number of deaths at a given temperature is lower now than it was four decades ago.”Related StoriesCardiac arrest survivor meets four Good Samaritans who saved his life one year after recoveryUNLV nutritionist explains how putting a halt on sweet treats affects the bodyCoffee may boost weight loss, concludes studyThe adaptation observed appears to be due to socioeconomic development and structural improvements–including improvements in housing conditions and health care systems. The authors highlighted a number of socioeconomic developments in Spain, including increases between 1991 and 2009 in per capita income (€8,700 to €22,880) and per capita health care spending (€605 to €2,182). In addition, between 1991 and 2011, the proportion of households with central heating went from 25.8% to 56.9% while the proportion of households with air conditioning rose from 4.16% in 1991 to 35.5% in 2008. Source:Barcelona Institute for Global Health (ISGlobal)Journal reference:Achebak, H. et al. (2019) Trends in temperature-related age-specific and sex-specific mortality from cardiovascular diseases in Spain: a national time-series analysis. The Lancet Planetary Health. doi.org/10.1016/S2542-5196(19)30090-7. The Spanish population has demonstrated a considerable capacity to adapt to rising temperatures. However, as this has not necessarily been the result of a strategy to mitigate the consequences of climate change, it is possible that this adaptive response is limited and will not be sustained at higher temperatures, as climate warming accelerates.”Joan Ballester, ISGlobal Researcher and Coordinator of the Study
Citation: Thousands of websites infected by ‘crypto mining’ malware (2018, February 12) retrieved 18 July 2019 from https://phys.org/news/2018-02-thousands-websites-infected-crypto-malware.html Researchers report a new kind of malware which operates in stealth mode to “mine” cryptocurrencies has infected at least 4,000 websites including those operated by government agencies The attack is the first major incident made public in which a new breed of hackers took over a large numbers of websites to effectively create currencies like bitcoin which are generated by using computing power.The attacks made public over the weekend by British security researcher Scott Helme showed more than 4,000 website were infected in this manner, including those of the British data protection and privacy watchdog and the US federal courts system.Unlike traditional attacks, these infections do not contain “ransomware” or steal data, but operate in stealth mode to make profits from the shadowy world of cryptocurrencies.Helme said in a blog post Sunday that the hackers were able to reach large numbers of websites by infecting a commonly used “plug-in,” or software which helps a site run better.In this case, the hackers used the malicious software to create Monero, one of several new cryptocurrencies which are making a splash in financial markets.”If you want to load a crypto miner on 1,000+ websites you don’t attack 1,000+ websites, you attack the 1 website that they all load content from,” he said.The creator of the plug-in, the British software firm TextHelp, said it took the affected software offline after it discovered the “attempt to illegally generate cryptocurrency. “”This was a criminal act and a thorough investigation is currently underway,” the company said in a statement. Researchers have been warning in recent weeks about this kind of malware, which can deliver profits without being obvious to users.Security researchers at Cisco Talos warned last month that this kind of hacking activity “has exponentially increased.”Because of the huge financial gains in cryptocurrencies, Cisco researchers said this has become a prime target for hackers.”At a high level mining is simply using system resources to solve large mathematical calculations which result in some amount of cryptocurrency being awarded to the solvers,” Cisco researchers wrote in a research note.Security researcher Graham Cluley said the latest attack highlights vulnerabilities in websites which may have weaknesses in third party components.”Things could have been much worse,” Cluley said in a blog post. “Imagine if the plug-in had been tampered with to steal login passwords rather than steal CPU resources from visiting computers.” This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Tech companies targeted by sophisticated malware attack Explore further © 2018 AFP Thousands of websites around the world, including many operated by governments, have been infected by hackers using the sites’ computing power to “mine” cryptocurrencies, security researchers said.
In a statement, the social media giants—which are both owned by Facebook—announced “new tools to help people manage their time” spent on the platforms.Among the tools are a way to limit notifications, and a dashboard that allows users to keep track of how much time they have spent on the platforms.”We want the time people spend on Instagram and Facebook to be intentional, positive and inspiring,” the statement said.”Our hope is that these tools give people more control over the time they spend on our platforms and also foster conversations between parents and teens about the online habits that are right for them,” it added.Facebook said it was introducing a daily reminder, whereby users are alerted when they reach the time limit they set for themselves to spend on the app.It is also introducing an option to deactivate notifications on smartphones.Facebook has in recent months introduced a string of changes to its content, including a major plan earlier this year to update its newsfeed to emphasise posts from friends and family.That shift had prompted fears it could drive away advertisers if people spent less time on the social network.Facebook founder Mark Zuckerberg had announced the changes in 2017, as his firm sought to respond to accusations that it encouraged addiction to its platform.Earlier this year, Zuckerberg said: “In 2018, we’re focused on making sure Facebook isn’t just fun to use, but also good for people’s well-being and for society.”Since the measures were introduced, viral videos have seen a significant drop in reach.The plan in turn saw a 5 percent drop in time spent on Facebook in the last quarter of 2017. Facebook and Instagram are introducing “new tools to help people manage their time” spent online Explore further Do you worry that you, or your children, spend too much time on social media? Facebook and Instagram on Wednesday said they want to help you take control. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. © 2018 AFP Citation: Facebook, Instagram to introduce time-management tools (2018, August 1) retrieved 18 July 2019 from https://phys.org/news/2018-08-facebook-instagram-time-management-tools.html Facebook sinking fast among US teens: survey
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further “Ryanair today (Thursday) confirmed that overnight it had reached agreement with FORSA union and its Irish pilots committee on behalf of Republic of Ireland based pilots,” the no-frills airline tweeted.Reports said that the union has recommended that the pilots back the deal, of which no details were disclosed.”Ryanair will take these proposals to its Board in due course after the Irish based pilots have voted on this signed agreement,” the tweet added.”The mediator… has asked both sides to refrain from further comment until the ballot has concluded and we will respect his wishes,” Ryanair continued.Earlier this month, Ryanair pilots across Europe staged a coordinated 24-hour strike to push their demands for better pay and conditions, plunging tens of thousands of passengers into transport chaos at the peak of the busy summer season.The Irish no-frills airline was forced to scrap some 400 out of 2,400 scheduled European flights as pilots in Ireland, Germany, Belgium, Sweden and the Netherlands walked off the job.Around 55,000 passengers were affected by the strikes, said Ryanair, which has offered customers refunds or the option of rebooking their journeys.Ryanair slammed the stoppages as “unnecessary” but pilots counter that the carrier has refused to engage in meaningful dialogue about collective labour agreements since it began recognising unions in December 2017.The airline meanwhile suffered a round of strikes by cockpit and cabin crew in July that disrupted 600 flights in Belgium, Ireland, Italy, Portugal and Spain, affecting 100,000 travellers. Ryanair strike hits 600 flights, 100,000 passengers Ryanair on Thursday said it had “reached agreement” with an Irish union representing pilots, in a move that could end strike action that has resulted in cancelled flights across Europe. © 2018 AFP Citation: Strike-hit Ryanair announces deal with Irish union (2018, August 23) retrieved 18 July 2019 from https://phys.org/news/2018-08-strike-hit-ryanair-irish-union.html The Irish no-frills airline was forced to scrap some 400 out of 2,400 scheduled European flights as pilots in Ireland, Germany, Belgium, Sweden and the Netherlands walked off the job
Explore further The century-old train car known to be the site of business transactions for the Ringling Bros. and Barnum & Bailey Circus has long been too fragile for visitors to step inside. The Wisconsin has faced conservation issues due to the discontinuation of spare train parts. Through a project led by the University of South Florida, it will no longer be limited to glancing through a window. Provided by University of South Florida “What we tried to ensure is that we are able to take real parts out of service so that perfect weight and appearance replicas can take their place,” said Celestin. “In so doing, we are able to further preserve the fragile antique components while being able to “adjust the slider” of time’s patina on an object—stopping at as little or much age-related damage as we want. This time-machine approach to preservation allows you to very easily create a model of how a part would look if brand new today, and also allow realistic, 3-D printed replacement parts to sit alongside their time-aged counterparts.”The Wisconsin was John Ringling’s personal train car that traveled the country, often accompanying the cast of his infamous circus come to be known as “The Greatest Show on Earth,” which ceased performance in May 2017. It changed hands throughout the 20th century, eventually landing at the Ringling Museum in Sarasota in 2003. Just prior, it underwent significant restoration to uncover the original paint, gold plating, and beautiful stain glass windows. Ornately carved picture frame was 3D-printed to allow for full digital access to the Wisconsin rail car, in which used alongside the Ringling Bros. and Barnum & Bailey Circus during the early 1900s. Credit: University of South Florida Citation: Ringling train chugs into digital world (2018, November 14) retrieved 17 July 2019 from https://phys.org/news/2018-11-ringling-chugs-digital-world.html John Ringling’s personal train car used in the early 1900s. Credit: The Ringling Museum Ringling elephants say goodbye to the circus Dr. Tanasi is founder of the Institute for Digital Exploration (IDEx) in the USF College of Arts and Sciences Department of History. IDEx also led a massive 3-D scanning project of the 36,000 square-foot Ca’d’Zan, the one-time residence of John and Mable Ringling.”The mission of IDEx to document, preserve, and protect cultural heritage aligns with that of The Ringling, which aims to collect, preserve, and exhibit art for the benefit of the public,” said David Berry, assistant director of academic affairs at The Ringling. “The technology employed by IDEx will be used to help The Ringling make its collections more accessible to visitors, on site and online.” This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. 3D-printed replacement of a train hook used on the Wisconsin, in which toured with the Ringling Bros. and Barnum & Bailey Circus in the early 1900s. Credit: University of South Florida During a presentation at the International Conference on Cultural Heritage and New Technologies in Vienna, Austria, Davide Tanasi, Ph.D., assistant professor of history, and Michael Celestin, Ph.D., senior research engineer, revealed 3-D models of the train, including its luxurious interior, providing full digital access.In order to make this happen, they used digital photogrammetry and terrestrial laser scanning to 3-D print furniture elements and metal components of the train undercarriage, allowing for the creation of spare parts for future restoration efforts. They printed using metal, wood and porcelain, closely mimicking the train built in 1896. It’s 79×14 ft and includes three states rooms, a kitchen, dining room, servants’ quarters and bathrooms.”The virtualization of the Wisconsin train car is the result of an innovative approach aimed to popularize through digital technology such crown jewel of Florida cultural heritage, currently partly accessible on site and basically digitally invisible for the remote public,” said Tanasi.
The unauthorized use of personal data is difficult to track. But blockchain can change that. Instead of hoarding the data of millions of users for large companies, each user can hold the keys for access to their data.Currently, there is no universal method to track who shared what, with whom, when and for what purposes in a verifiable fashion. My current research addresses these problems by incorporating the blockchain technology. Blockchain has already proven its huge influence on the financial world with its first application in the form of cryptocurrencies such as Bitcoin. It might not be long before its impact is felt everywhere. Blockchain is a secure chain of digital records that exist on multiple computers simultaneously so no record can be erased or falsified. The redundancy of the system ensures many backups, and the lack of a central storage place ensures there is no one target for hackers. Some suggest that blockchain could become a component of the next generation of the internet.Many blockchain systems provide a technology called “smart contract:” these are the rules by which records can be accessed and modified by creating new versions. These rules define, for example, who gets access to the stored records, under what conditions, for what declared purpose and in exchange of what (payment or virtual credit). Smart contracts also record every access to the data in the blockchain.In this way, users can permanently and securely store their data, set their own conditions and control who accesses the data and for what purpose. Because of these features, blockchain technology can be used to store user profile data.Hoarding the dataCurrently, social media giants hoard user data and use it to sell targeted advertisements (their main source of revenue). These social media networks don’t give users a real choice or awareness of what data about them are kept. They provide very few control options and no rewards for users in exchange of their data.Recently, we have seen many cases when user data has been stolen by hackers, leading to breaches of privacy, the possibility for identity theft or exploitation of the data to manipulate people and influence public opinion towards voting. This can have serious consequences for the democratic process in a liberal society. User-controlled privacyOne of the elements of user data sharing would be to control who can share the data and by what means, and how users can be incentivized to share data. Smart contracts allow storing these access-control policies securely on the blockchain. Blockchain provides an unalterable record of all transactions. Users can also be incentivized with monetary rewards for sharing their data to commercial enterprises.I have been researching how a blockchain-based system can keep users data safe, provide access control and provenance of their ownership, and incentivize them to share their data. My recent paper, presented at the International Conference on Blockchain in Seattle in March 2018, is the first in the area of sharing research data and it generated a lot of interest.University of Saskatchewan professor and computer scientist Julita Vassileva has worked on ways that allow users to control the sharing of their data, and also provide incentives that preserve a user’s control and provide incentives for sharing. Vassileva’s guidance and supervision led me to experiment with blockchain technology to implement such a framework. This led to an award-winning research paper, that I presented at the 2017 Future Technologies Conference. The paper proposed a blockchain-based system to share users’ personal data among tourism businesses.Sharing can be caringWe need new data-sharing practices so that we can maximize what we learn from research. In medicine and health care, for example, both personalized patient care and medical research can benefit from sharing research data from clinical trials.Similar to shifts in the business world, the personalization of services is trending. Various data associated with users’ profiles and behaviours are being shared among commercial enterprises. This information is used to better help businesses target their customers and improve the quality of their services. Much of the data are contributed voluntarily by the user; others are obtained from observation of user activities, or inferred through advanced analysis of volunteered or observed data.Users need to become active participants who stand to benefit from the personal data economy. Blockchain and smart contracts can support users in the following ways:Give the users full transparency over who accesses their data, when and for what purpose;Allow the users to specify the purposes of data sharing, which kinds of data that can be shared, and which applications or companies can access the data;Provide an incentive to users for sharing their data (in terms of payment for the use of the data by applications, as specified by the contracts).My research project develops guidelines and methods for embedding privacy, user transparency, control and incentives from the start in the design of a data sharing framework. This is an alternative to what currently exists, providing a platform that users can trust to protect their data, have control over it and share it in the ways they want. Blockchain technologies can empower people by allowing them more control over their user data. Credit: Shutterstock Provided by The Conversation This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Protecting the ‘right to be forgotten’ in the age of blockchain This article is republished from The Conversation under a Creative Commons license. Read the original article. Explore further Citation: Transparency and privacy: Empowering people through blockchain (2019, January 16) retrieved 17 July 2019 from https://phys.org/news/2019-01-transparency-privacy-empowering-people-blockchain.html
Explore further Citation: Artificial intelligence can predict premature death, study finds (2019, March 27) retrieved 17 July 2019 from https://phys.org/news/2019-03-artificial-intelligence-premature-death.html Journal information: PLoS ONE Credit: CC0 Public Domain More information: Stephen F. Weng et al. Prediction of premature all-cause mortality: A prospective general population cohort study comparing machine-learning and standard epidemiological approaches, PLOS ONE (2019). DOI: 10.1371/journal.pone.0214365 , journals.plos.org/plosone/arti … journal.pone.0214365Stephen F. Weng et al. Can machine-learning improve cardiovascular risk prediction using routine clinical data?, PLOS ONE (2017). DOI: 10.1371/journal.pone.0174944 Provided by University of Nottingham Computers which are capable of teaching themselves to predict premature death could greatly improve preventative healthcare in the future, suggests a new study by experts at the University of Nottingham. Artificial intelligence can accurately predict future heart disease and strokes, study finds The team of healthcare data scientists and doctors have developed and tested a system of computer-based ‘machine learning’ algorithms to predict the risk of early death due to chronic disease in a large middle-aged population.They found this AI system was very accurate in its predictions and performed better than the current standard approach to prediction developed by human experts. The study is published by PLOS ONE in a special collections edition of “Machine Learning in Health and Biomedicine”.The team used health data from just over half a million people aged between 40 and 69 recruited to the UK Biobank between 2006 and 2010 and followed up until 2016.Leading the work, Assistant Professor of Epidemiology and Data Science, Dr. Stephen Weng, said: “Preventative healthcare is a growing priority in the fight against serious diseases so we have been working for a number of years to improve the accuracy of computerised health risk assessment in the general population. Most applications focus on a single disease area but predicting death due to several different disease outcomes is highly complex, especially given environmental and individual factors that may affect them.”We have taken a major step forward in this field by developing a unique and holistic approach to predicting a person’s risk of premature death by machine-learning. This uses computers to build new risk prediction models that take into account a wide range of demographic, biometric, clinical and lifestyle factors for each individual assessed, even their dietary consumption of fruit, vegetables and meat per day.”We mapped the resulting predictions to mortality data from the cohort, using Office of National Statistics death records, the UK cancer registry and ‘hospital episodes’ statistics. We found machine learned algorithms were significantly more accurate in predicting death than the standard prediction models developed by a human expert.”The AI machine learning models used in the new study are known as ‘random forest’ and ‘deep learning’. These were pitched against the traditionally-used ‘Cox regression’ prediction model based on age and gender—found to be the least accurate at predicting mortality—and also a multivariate Cox model which worked better but tended to over-predict risk.Professor Joe Kai, one of the clinical academics working on the project, said: “There is currently intense interest in the potential to use ‘AI’ or ‘machine-learning’ to better predict health outcomes. In some situations we may find it helps, in others it may not. In this particular case, we have shown that with careful tuning, these algorithms can usefully improve prediction.”These techniques can be new to many in health research, and difficult to follow. We believe that by clearly reporting these methods in a transparent way, this could help with scientific verification and future development of this exciting field for health care.”This new study builds on previous work by the Nottingham team which showed that four different AI algorithms, ‘random forest’, ‘logistic regression’, ‘gradient boosting’ and ‘neural networks’, were significantly better at predicting cardiovascular disease than an established algorithm used in current cardiology guidelines. This earlier study is available here.The Nottingham researchers predict that AI will play a vital part in the development of future tools capable of delivering personalised medicine, tailoring risk management to individual patients. Further research requires verifying and validating these AI algorithms in other population groups and exploring ways to implement these systems into routine healthcare. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Irish no-frills airline Ryanair on Monday warned of further profits turbulence after annual earnings slumped almost a third, mainly on cheaper fares triggered by overcapacity in the European short-haul sector. Ryanair’s profits were hit by falling ticket prices, but passenger numbers were up Profit after tax dropped 29 percent to 1.02 billion euros ($1.14 billion) in the year ending March 31 compared with a year earlier, also on higher fuel and staff costs, the Dublin-based carrier said in an earnings statement.Ryanair said net profits could decline further in 2019/20, to between 750 million and 950 million euros.”Short-haul capacity growth and the absence of Easter in the fourth quarter led to a six percent fare decline,” chief executive Michael O’Leary said in the statement.However the drop in fares attracted more passengers, whose numbers climbed nine percent to 142 million for the year.Europe’s short-haul sector is being weighed down by fierce competition despite some consolidation, including Ryanair’s recent purchase of Austrian carrier Lauda. “We expect further consolidation and airline failures in winter 2019 and again into 2020 due to over-capacity, weaker fares, and higher oil prices,” Ryanair said Monday.After falling sharply following the results update, shares in Ryanair recovered to trade down 0.4 percent at 10.76 euros in Dublin stock market business.”Fares down, traffic up, costs jumping—more of the same kind of themes we’ve been seeing for a number of quarters from Ryanair and for the whole European airline sector,” noted Neil Wilson, chief market analyst at Markets.com.Ryanair’s profits update comes as the airline undergoes major restructuring.Mirroring a set-up by British Airways and Iberia owner IAG, Ryanair aims to have four distinct operations, each with its own chief executive.Under overall boss O’Leary will be Ryanair DAC overseeing the Irish operations, Ryanair UK, Lauda for its Austrian business and Ryanair Sun, or Polish unit, according to an announcement earlier this year.Higher costsRyanair’s recent performance has been hit also by pan-European strikes last year that forced it to cancel flights, affecting thousands of passengers, and offer improved pay deals to staff via landmark deals with unions.The airline on Monday said last year’s staff costs jumped by 200 million euros on pay increases for staff, notably pilots.Ryanair is also exposed to any Brexit fallout, with Britain accounting for about one-quarter of its revenues.The airline on Monday said the outlook for its current financial year was in part dependent on “no negative Brexit developments”.Ryanair’s fierce rival EasyJet on Friday said the British airline’s net losses more than quadrupled in its first half on “tough” market conditions and high fuel costs.The carrier also warned that its second-half performance would encounter turbulence, partly because of Brexit turmoil and Europe’s economic slowdown. Citation: Ryanair sees more turbulence after profit slumps on cheaper fares (2019, May 20) retrieved 17 July 2019 from https://phys.org/news/2019-05-ryanair-profit-slumps-cheaper-fares.html Explore further Ryanair blames lower fares for fresh profit warning © 2019 AFP This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
Professor ZHENG Zijian leads the research team of PolyU’s Institute of Textiles and Clothing to develop the highly flexible, high-energy Textile Lithium Battery. Credit: PolyU Applying PolyU’s patented novel technology of Polymer-Assisted Metal Deposition (PAMD), highly conductive metal, copper (Cu) and nickel (Ni) are uniformly and conformally deposited onto pre-treated fabrics. Such fabricated metallic fabrics, featuring low sheet resistance and large surface area , serve as current collectors in battery. After adding active materials to act as cathode and anode, the metallic fabrics, together with separator and electrolyte, are assembled into the Textile Lithium Battery. Provided by Hong Kong Polytechnic University Credit: Hong Kong Polytechnic University Citation: Team develops highly flexible high-energy textile lithium battery for wearable electronics (2019, May 27) retrieved 17 July 2019 from https://phys.org/news/2019-05-team-highly-flexible-high-energy-textile.html PolyU’s novel lightweight Textile Lithium Battery demonstrates high energy density of more than 450 Wh/L, and excellent flexibility—with a bending radius of less than 1mm, and foldability of over 1,000 cycles with marginal capacity degradation. In comparison, the existing bendable lithium battery can only reach a bending radius of about 25 mm, and with much lower performance of less than 200 Wh/L. The Textile Lithium Battery, of less than 0.5 mm thick, also possesses fast charging/discharging capability, and long cycle life comparable with conventional lithium batteries.[Please refer to the Annex for detailed comparison of performance between PolyU’s Textile Lithium Battery and other batteries] This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Novel technology aims to improve lithium metal battery life, safety The innovation developed by the research team of PolyU’s Institute of Textiles and Clothing (ITC) has snatched three prizes at the 47th International Exhibition of Inventions of Geneva held in April this year, namely a Gold Medal and two Special Merit Awards.Professor ZHENG Zijian, who leads the ITC research team, said, “Wearable technology has been named as the next global big market opportunity after smartphones. Global market revenues for wearable devices are forecast to grow by leaps and bounds, of over 20% annually, to reach US$100 billion by 2024. As all wearable electronics will require wearable energy supply, our novel technology in fabricating Textile Lithium Battery offers promising solution to a wide array of next-generation applications, ranging from healthcare, infotainment, sports, aerospace, fashion, IoT [Internet of Things] to any sensing or tracking uses that may even exceed our imagination of today.”Lithium battery is currently the dominant rechargeable battery in the market due to its relatively high energy density and long cycle life. As conventional bulky heavy lithium battery is hard for use in wearable devices, over the past decade, scientists have put in efforts in developing bendable lithium battery, often by using metal foils as current collectors. However, it is only until the emergence of PolyU’s Textile Lithium Battery that the bottlenecks over energy density, flexibility, mechanical robustness and cycling stability being able to be addressed. Laboratory tests conducted by the ITC team have proven the extremely high mechanical stability, durability and safety of the Textile Lithium Battery under deformation. When the battery is repeatedly folded in half, twisted at different angles or freely crumpled, its voltage window remained unchanged. Bending test showed that the battery can be bent over 1,000 times with marginal capacity degradation. Safety tests conducted by continuous hammering, trimming with scissors and penetrating with nail proved the battery can stably provide power output for the electronic components with no risk of catching fire or bursting. Explore further
Creative Genius: The World’s Greatest Minds Hidrogen Peroksida dicampur katalis Potasium Iodida akan mengalami dekomposisi yg sangat cepat. Kakak2 Kimia mudah2an mau bantu menjelaskan lebih detail. pic.twitter.com/AN6kjvzyNc — Semesta Sains (@semestasains) June 7, 2019 An instructor and two children pour three cups of powder into a bin of red liquid. Suddenly — poof — a cloud of what looks like cotton candy explodes toward the ceiling. This popular video on Twitter comes courtesy of the Malay-language account w, which shares science content. But what is going on in the video? It’s a rather dangerous version of a classic chemistry demonstration, according to Brian Hostetler, an educator at the Denver Museum of Nature & Science. The reaction is typically known as “elephant’s toothpaste,” due to its foamy appearance, and it’s commonly used in chemistry classrooms to explain catalysts, Hostetler told Live Science. [Elementary, My Dear: 8 Little-Known Elements]These Sharks Were Too Busy to Notice a Bigger Predator Watching ThemThe unexpected twist at the end of this feeding frenzy delighted scientists.Credit: NOAA Office of Ocean Exploration and Research, Windows to the Deep 2019Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Headbutting Tiny Worms Are Really, Really Loud00:35关闭选项Automated Captions – en-US facebook twitter 发邮件 reddit 链接https://www.livescience.com/65793-cotton-candy-explosion-explained.html?jwsource=cl已复制直播00:0002:2802:28 Easy but explosive The reaction uses cheap, easy-to-access ingredients: hydrogen peroxide, dish soap, potassium iodide and food coloring. Hydrogen peroxide is key. It’s made up of two hydrogen and two oxygen molecules. The bonds between these molecules naturally break, so over time, hydrogen peroxide slowly becomes water and oxygen gas. That reaction happens faster when exposed to light, Hostetler said, which is why hydrogen peroxide is sold in brown bottles. Normally, the slow breakup (or decomposition, in chemistry terms) of hydrogen peroxide into water and oxygen is unnoticeable. But the elephant’s toothpaste experiment speeds the process with a catalyst, a chemical compound that increases the rate of a given reaction. Potassium iodide — a salt of iodine, and the dietary supplement that’s used to add iodine to table salt — provides that catalyst. “In the presence of potassium iodide, hydrogen peroxide decomposes almost immediately,” Hostetler said. The setup is simple. Hydrogen peroxide is mixed with dish soap, and food coloring is often added for a dramatic effect (which explains the cotton-candy pink in the Twitter video). The potassium iodide is added, and the iodide ion that’s part of that compound attracts the oxygen in the hydrogen peroxide, breaking the bonds and rapidly transforming the hydrogen peroxide into water and oxygen gas. The oxygen molecules then get trapped by the soap, forming bubbles, Hostetler said. In a step sometimes added to the elephant’s toothpaste demonstration, a glowing splint — a strip of wood that is hot but not burning — that is inserted into the bubbles will catch alight, sparked by the pure oxygen. Toning it down Usually, Hostetler said, the elephant’s toothpaste experiment creates an oozy concoction. So why did the Twitter version send bubbles flying toward the ceiling? That particular reaction was due to the strength of the ingredients and the shape of the containers, Hostetler said. A fairly safe version of the elephant’s toothpaste demonstration can be done at home with 3% hydrogen peroxide bought from the drugstore, with yeast as the catalyst (yeast contains the enzyme catalase, which also breaks down bonds in hydrogen peroxide). The combination will ooze and get a little warm as the reaction releases heat, but other than the need to take care not to touch the “toothpaste,” as hydrogen peroxide can be irritating to skin and eyes, this DIY version is pretty safe. The Twitter video probably shows the reaction with 30% hydrogen peroxide, or even stronger, Hostetler said. The demonstrator also uses potassium iodide that’s in powder form instead of mixed into water. And he has it poured in three batches at once into a large container with a lot of surface area, so the reaction happens across a large amount of hydrogen peroxide all at one time. That makes the scene in the video “super-duper dangerous,” Hostetler said. Thirty percent or higher hydrogen peroxide can cause chemical burns on the skin, he said, and the reaction could heat the solution by hundreds of degrees. It’s that heat and steam from the reaction that floats some of the foam skyward in the Twitter video. The bottom line, Hostetler said, is not to try the jumbo version of the demonstration at home – but feel free to press “play” again on Twitter. “It’s a cool video,” he said. Wacky Physics: The Coolest Little Particles in Nature Bagaikan mengundang iblis dari neraka tanpa mantra, reaksi ini disebut “The Elephant’s Toothpaste”. Top 10 Greatest Explosions Ever Originally published on Live Science.
Osteoporosis is a common disease that makes bones weak, thin, brittle and more likely to break. The condition typically occurs in women after menopause and can increase the risk of fractures, especially in the hip, spine and wrist, according to the National Institutes of Health. The condition is often called a “silent disease” because bone loss can happen slowly and without any warning signs. People may not be aware they have osteoporosis until they break a bone, lose height or develop hunched posture. About 10 million Americans have osteoporosis, and another 44 million have low bone mass, or osteopenia, placing them at increased risk for osteoporosis, according to the National Osteoporosis Foundation.Advertisement There are a number of factors that may lead to osteoporosis, said Dr. Harold Rosen, an endocrinologist and director of the Osteoporosis Prevention and Treatment Center at Beth Israel Deaconess Medical Center in Boston. One such factor is the accelerated bone loss that occurs after menopause, he said. Men also lose bone as they age, normally once they’re in their 60s and 70s, Rosen said. Some men think osteoporosis affects only women, but it strikes men too, he explained. Low calcium intake and low vitamin D levels in the body can also lead to bone loss, Rosen told Live Science. The body needs a good supply of calcium and other minerals to form bone, and vitamin D helps absorb calcium from food and incorporate the nutrient into bone. In addition, unhealthy habits, such as smoking and excessive drinking, can speed up bone loss, he said. Bone Density Decreases in SpaceBone loss is a serious issue that has plagued astronauts since the dawn of the Space age. In the microgravity environment bones are remodeled with a decrease in mineral density. Good nutrition, increased vitamin D intake and exercise are used to battle the issue aboard the ISS.Volume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Better Bug Sprays?01:33关闭选项Automated Captions – en-US facebook twitter 发邮件 reddit 链接https://www.livescience.com/65900-osteoporosis.html?jwsource=cl已复制直播00:0002:4102:41Your Recommended Playlist01:33Better Bug Sprays?01:08Why Do French Fries Taste So Bad When They’re Cold?04:24Sperm Whale Befriends Underwater Robot00:29Robot Jumps Like a Grasshopper, Rolls Like a Ball00:29Video – Giggly Robot02:31Surgical Robotics关闭 How bone changes over time The body is continually breaking down small areas of old bone tissue, a process called bone resorption, and replacing that old tissue with new bone tissue. During childhood and adolescence, new bone is deposited faster than old bone is removed. This makes bones larger, heavier and denser. Peak bone mass, or when bones reach their maximum density and strength, typically occurs around age 30 for both sexes. Around age 35, bone breakdown occurs faster than the replacement by new bone, causing a gradual loss of bone mass, according to the National Institute on Aging. Women undergo more-rapid bone loss in the first few years after menopause (around age 51) than in their 30s and 40s because the ovaries produce much less estrogen, a hormone that protects against bone loss, according to The American College of Obstetricians and Gynecologists. Men in their 50s and 60s also start to lose bone mass, but at a slower rate than women do. It’s not until ages 65 to 70 that men and women begin losing bone mass at about the same rate. For that reason, osteoporosis is more common in women. The condition affects about 25% of women and 5% of men ages 65 and over, according to the Centers for Disease Control and Prevention. Can osteoporosis be prevented? The more bone a person builds early in life, the better that individual can resist bone loss later on. Prevention should start when people are younger, during their peak bone-building years, with the following steps, according to the National Osteoporosis Foundation: Medications: Using certain drugs on a long-term basis can lead to bone loss. These medicines include corticosteroids, such as prednisone; heparin, a blood thinner; selective serotonin reuptake inhibitors (SSRIs), a class of antidepressants; and aromatase inhibitors, used to treat breast cancer. Osteoporosis risk factors The following factors can increase a person’s risk of developing osteoporosis, according to the Cleveland Clinic. Family history: People whose parents had a hip fracture may be more likely to develop the disease. Download a helpful brochure from Osteoporosis Canada on managing osteoporosis through exercise. Osteoporosis treatment and medications People with advanced osteopenia as well as those with osteoporosis need medication to reduce their risk of fractures. Bisphosphonates are usually the first drugs used to treat osteoporosis, but while they help slow bone loss, they don’t help build new bone. These drugs include alendronate (Fosamax), risedronate (Actonel) and ibandronate (Boniva). Studies have shown that alendronate can reduce the risk of spine and hip fractures by up to 50%, Rosen said. Once a person has started treatment for osteoporosis, bone-density testing should be repeated every two to three years to monitor how the density is changing and whether treatment is working, Rosen said. For severe osteoporosis, patients may need one of three medications given by injection that actually build new bone, Rosen said. These include teriparatide (Forteo), abaloparatide (Tymlos) and romosozumab (Evenity). But after a year on these bone-building drugs, a patient needs to take bisphosphonates; otherwise, all the bone-density gains will be lost, Rosen said. In addition to medication, people with osteoporosis should aim to include 1,200 milligrams of calcium a day in their diet, from food or supplements (preferably calcium citrate), Rosen said. He also recommends taking 1,500 to 2,000 International Units (IU) of supplemental vitamin D each day. Being physically active is also beneficial for people with osteoporosis. Rosen recommends regular workouts that include weight-bearing aerobic activity, as well as strength training, balance and posture exercises. Additional resources: Medical problems: Numerous health conditions and diseases can also increase a person’s risk for osteoporosis. Osteoporosis bones are porous and weak compared to healthy bones that are more dense. Credit: Shutterstock Ethnicity: White and Asian women have the highest risk of osteoporosis, while African American and Hispanic women have a lower risk. Maintaining a healthy lifestyle, such as avoiding smoking and limiting alcohol consumption, reduces bone loss. Getting regular weight-bearing exercise. Review this list of calcium-rich foods from the University of California, San Francisco Medical Center. Osteoporosis symptoms and diagnosis Osteoporosis may cause no symptoms in its early stages, and as a result, the disease can go unnoticed for decades. Some visible signs of osteoporosis may be a loss of height and a curve in the upper back, which may cause stooped posture. A “dowager’s hump” may occur when several vertebrae collapse from osteoporotic fractures in the spine. Other symptoms may include back pain, from a fracture or a collapsed vertebra in the spine, or tooth loss, if osteoporosis has affected the jawbone. Hip fracture is another serious consequence of osteoporosis. About 20% of older adults who fracture a hip die within one year from complications of the broken bone or the surgery needed to repair it, according to the National Osteoporosis Foundation. Doctors may perform a bone mineral density (BMD) test to determine if a patient has osteoporosis, according to the Mayo Clinic. The test uses a special X-ray machine to measure the mineral content at three different bone sites, typically the hip, the spine and the top of the femur. The scan can reveal if a person has low bone mass at any of these three bone sites by comparing the patient’s bone density to the normal bone density in a healthy 30-year-old person of the same sex. BMD testing is recommended for women who are 65 or older and for women 50 to 64 who have certain risk factors for the disease. Men over the age of 70 or younger men with risk factors should also be screened for osteoporosis. Learn more about osteoporosis in men from the National Institutes of Health. Sex: Women are more likely to develop osteoporosis than men, because women have less bone tissue and lose bone faster after menopause. Nutrition: Eating a diet that’s low in calcium and vitamin D increases osteoporosis risk. Being a couch potato: Not getting enough physical activity or too much bed rest following an injury, illness or surgery weakens bones over time. Weight-bearing exercise can help keep bones strong and prevent or slow osteoporosis progression. Credit: Shutterstock Unhealthy habits: Smoking and consuming too much alcohol can both increase bone loss. Body size: Petite and thin people are at greater risk of this condition because they have less bone to lose than people with larger frames and more body weight. Age: Bones typically become thinner and weaker with age. Consuming adequate amounts of foods rich in calcium and vitamin D throughout life. This article is for informational purposes only and is not meant to offer medical advice.
SHARE SHARE SHARE EMAIL COMMENT Published on COMMENTS Our Bureau In a setback for rebel AIADMK leader TTV Dhinakaran, the Madras High Court on Thursday upheld the disqualification of 18 AIADMK MLAs who had last year revolted against Chief Minister Edappadi K Palaniswami. The judgment came as a major relief for the ruling AIADMK government, which could have faced an existential crisis had the ruling been in favour of the disqualified MLAs. The 18 seats will now become vacant and require by-elections. Setback for Dhinakaran Reacting to the judgment, a visibly disappointed Dhinakaran told reporters he will consider the next course of action after holding discussions with the MLAs. He has two options: appeal against the order in the Supreme Court or face the by-elections for the 18 seats. AIADMK supporters were jubilant over the verdict. “Justice prevailed. We are ready to face by-polls for the 18 Assembly constituencies. AIADMK will win all the seats in the by-election,” tweeted Palaniswami.In his 475-page order, Justice M Sathyanarayanan said: “There is no error apparent on the face of the record and the reasons assigned by the Speaker did not suffer on the grounds of breach of constitutional mandate…and no perversity is attached to the reasons assigned by the Speaker to disqualify the petitioners.”In August 2017, the 18 MLAs belonging to the faction led by Dhinakaran then met Governor C Vidyasagar Rao, saying they were withdrawing support to Palaniswami, but not to the AIADMK government. Following this, the Speaker disqualified them under the anti-defection law.The MLAs appealed their disqualification. On June 14 this year, the First Bench of the Madras High Court gave a split verdict. The Supreme Court then appointed a third judge to hear the case. 0 October 25, 2018
The Board of Intermediate Education (BIE), Telangana, has claimed that the 22 failed who committed suicide had ‘poor’ academic track record.The reverification of these students confirmed their result status as failed, it said in a statement. It may be recalled that large- scale discrepancies surfaced in the Intermediate exam results announced by the BIE on April 18. Apart from triggering protests across the State, some students who failed resorted to the extreme step.In a statement, the BIE said that out of 25 such students, 14 had failed in more than one subject while one student has committed suicide even after passing the exam with Grade A.Re-verification results will be announced before May 10. IT firm Globarena, which was found responsible for the errors in data processing (by the investigating panel) has been kept out of the reverification process. The ongoing re-verification is being supervised by the Centre for Good Governance (CGG) and the Jawaharlal Nehru Technological University (JNTU), Hyderabad.Of the 7.9 lakh students who appeared for the examinations, 3.28 lakh were declared failed by the BIE. COMMENT education Published on SHARE SHARE EMAIL test/examination Telangana SHARE COMMENTS May 06, 2019